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呼吸系统PDF|Epub|txt|kindle电子书版本网盘下载
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- (英)戴维斯,(英)穆瑞斯主编 著
- 出版社: 北京:北京大学医学出版社
- ISBN:9787565901171
- 出版时间:2011
- 标注页数:171页
- 文件大小:79MB
- 文件页数:180页
- 主题词:呼吸系统疾病-医学院校-教材-英文
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图书目录
1 INTRODUCTION1
Introduction2
What is respiration?2
The need for respiration2
Diffusion in respiration and the circulation3
Timing in the circulation and respiration3
Basic science of respiration3
Drugs9
2 STRUCTURE OF THE RESPIRATORY SYSTEM,RELATED TO FUNCTION11
Introduction12
The upper airways12
The intrathoracic airways15
Blood vessels18
Pulmonary hypertension18
The lymphatics19
The nerves19
Gross structure of the respiratory system19
Pleurisy20
The diaphragm and chest wall20
How breathing is brought about22
Embryology23
Air-conditio ning24
Metabolic activity26
Metabolism of circulating biologically active substances27
Non-respiratory functions27
3 ELASTIC PROPERTIES 0F THE RESPIRATORY SYSTEM29
Introduction30
Intrapleural pressure(Ppl)30
Static lung compliance(CL)31
The effect of disease32
The physical basis of lung compliance32
4 AIRFLOW IN THE RESPIRATORY SYSTEM41
Introduction42
How airflow is brought about42
The nature of airflow43
The major determinant of flow-radius43
Airways resistance and obstructive pulmonary disease43
The clinical situation45
Sites of airways resistance46
Asthma and airways smooth muscle48
Bronchomotor tone49
Pharmacological treatment of asthma50
Clinical definitions50
Bronchitis and mucus52
Emphysema and radial traction53
Intrapleural pressure and cough54
Clinical tests for changes in resistance57
Work of breathing57
5 VENTILATION OF THE RESPIRATORY SYSTEM:THE IMPORTANCE OF ITS LACK OF UNIFORMITY IN DISEASE61
Introduction62
Spirometric abnormalities in disease63
Uneven distribution64
Dead space64
Alveolar dead space in disease65
The Bohr equation66
Factors affecting physiological dead space68
Alveolar ventilation and respiratory exchange68
The alveolar gas equation69
Distribution of inspired gas69
Other factors influencing distribution72
6 GAS EXCHANGE BETWEEN AIR AND BLOOD:DIFFUSION77
The path from air to tissue78
Lung disease and diffusion79
Fick's Law of Diffusion79
Measuring transfer factor82
Treating diffusion difficulties83
Carbon dioxide and other gases83
7 THE PULMONARY CIRCULATION:BRINGING BLOOD AND GAS TOGETHER85
The functions of the pulmonary circulation86
The anatomy of the pulmonary circulation86
Matching ventilation and perfusion89
Distribution of blood flow through the lungs89
Regional differences in ventilation in the lungs94
Ventilation/perfusion matching and its effect on blood O2 and CO2 content95
Shunt97
8 CARRIAGE OF GASES BY THE BLOOD AND ACID/BASE BALANCE99
Introduction100
Oxygen transport100
Dissolved oxygen:do we really need Hb and why keep it in red cells?108
Carbon dioxide transport109
Acid-base balance113
9 CHEMICAL CONTROL OF BREATHING119
Introduction120
Oxygen lack120
Carbon dioxide excess125
10 NERVOUS CONTROL OF BREATHING129
Introduction130
The rhythm generator131
Pattern of breathing in COPD132
The respiratory ' centres'133
The medullary groups133
Conscious control of breathing134
Respiratory muscle innervation135
Neuromuscular disorders137
Vagal reflexes137
Dyspnoea140
Other reflexes140
11 LUNG FUNCTION TESTS:MEASURING DISABILITY143
Introduction144
Spirometry144
Flow measurements145
Plethysmography145
Lung mechanics146
Transfer factor(diffusing capacity)147
Blood gases148
Gas washouts148
Exercise testing150
Challenge tests151
Appendix:some basic science153
Glossary159
Index165