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Protein metabolism．Some problems brought into focus＆Opening remarks by A．QUERIDO1

Action of hormones at the cellular level8

The effect of growth hormone on protein synthesis＆by A．KORNER8

Discussion:Dreyfus，Korner，Laron，Staehelin22

Regulation of protein synthesis by androgens and estrogens＆by J．D．WILSON26

Discussion:Aschkenasy，Kassenaar，Korner，Wilson41

Histological aspects of the action of androgens and oestrogens＆by J．A．SZIRMAI45

Discussion:Aschkenasy，Desaulles，Leathem，Querido，Szirmai，Tanner75

General Discussion:78

Introduction:The importance of experimental conditions for the demonstration of hormone effects in vitro and in vivo＆by W．DIRSCHERL78

Arias，Korner，Laron，Leathem，Querido，Raben，Szirmai，Tuchmann-Duplessis，Wilson86

Factors influencing protein metabolism in the organism90

Protein malnutrition and replenishment with protein in man and animals＆by J．C．WATERLOW90

Discussion:Aschkenasy，Fraser，Hoffenberg，Querido，Rundles，Schreier，Waterlow105

The bearing of the plane of nutrition on growth and endocrine development＆by R．A．McCANCE and E．M．WIDDOWSON109

Discussion:Bauer，McCance，Prader，Schreier Tanner，Waterlow118

Metabolic effects of growth hormone in man＆by M．S．RABEN，P．R．MINTON，M．L．MITOHELL，and H．JUAREZ-PENALVA121

Discussion:Ikkos，Querido，Raben，Young134

Nitrogen balance studies:the relation of protein metabolism to excessive shifts of sodium and potassium＆by P．S．BLOM，J．DE GRAEFF，A．A．H．KASSENAAR，and H．A．SONNEVELDT137

Studies of protein metabolism in humans with the aid of N15-labelled glyeine＆by A．HAAK，A．A．H．KASSENAAR，and A．QUERIDO150

Discussion:Blom，Fraser，Haak，kassenaar，Querido，Tremolières，Waterlow158

General Discussion:161

Introduction:Homoeostasis in protein metabolism＆by J．TREMOLIEBES161

Ikkos，Laron，Prader，Raben，Schreier，Staehelin167

Evaluation and mode of action of anabolic steroids170

Differentiation of action of various anabolic steroids＆by P．A．DESAULLES and C．KRAHENBUHL179

Evaluation of long-acting anabolic steroids＆by G．A．OVERBEEK，J．VAN DER VIES，and J．DE VISSER185

Discussion:Aschkenasy，Desaulles，Fraser，Gross，Kassenaar，Korner，Overbeek，Querido，Raben196

The influence of nutrition and nutritional status on the effect of androgens and anabolic agents＆by J．H．LEATHEM202

Discussion:Korner，Leathem，Overbeek，Querido，Sala，Waterlow，Young219

Effects of anabolic steroids on nucleic acid and protein metabolism＆by A．A．H．KASSENAAR，A．QUERIDO，and A．HAAK222

Discussion:Arias，Dirscherl，Dreyfus，de Jongh，Kassenaar，Korner，Overbeek，Querido，Szirmai，Tremolières，Wilson234

Effect of steroids on bone formation＆by K．KOWALEWSKI238

Discussion:Desaulles，Dymling，Gross，Kowalewski，Laron，Overbeek，Vermeulen263

General Discussion:268

Introduction:Effects of protein deficiency on the endoerine system＆by A．ASCHKENASY268

Aschkenasy，Desaulles，Dreyfus，Gross，Overbeek，Querido，Tanner，Vermeulen272

Protein metabolismm in human pathological states275

The effect of injury upon human protein metabolism＆by J．M．KINNEY275

Discussion:Fraser，Gemzell，Ikkos，Kinney，McCance，Tuchmann-Duplessis，Young297

Human liver cirrhosis secondary to nutritional deficiency＆by R．SUBRAMANLAM300

Discussion:Arias，Hoffenberg，Kowalewski，Prader，Subramaniam，Tremolières，Waterlow310

I131-albumin metabolism in human adults after experimental protein depletion and repletion＆by R．HORRENBERG，S．SAUNDERS，G．C．LINDER，E．BLACK，and J．F．BROOK314

Discussion:Arias，Aschkenasy，Fraser，Hoffenberg，Ikkos，Querido，Schreier，Waterlow323

Muscular protein metabolism in normal and diseased states＆by J．-C．DREYFUS，J．KRUH，and G．SCHAPIRA326

Discussion:Arias，Dreyfus，Kassenaar，Korner，Prader，Querido，Stachelin350

General Discusson:352

Introduction:Some aspcets of protein metabolism in surgical trauma and injury＆by K．SCHREIER352

Blom，Dreyfus，Kinney，Korner，Querido，Rittenberg，Sohreier，Tremolières，Waterlow，Wilson，Young355

The effects of anabolic agents in man361

The evaluation of growth and maturity in children＆by J．M．TANNER361

Use of anabolic agents in disorders of growth＆by A．PRADER and R．ILLIG383

Discussion:Gemzell，Haak，Laron，Prader，Querido，Raben，Tanner，van der Werff tan Bosch398

Definition，aetiology，and effects of osteopenia＆by G．C．H．BAUER405

Anabolic steroids in the treatment of osteopenia＆by J．-F．DYMLING，B．ISAKSSON，and B．SJOGREN412

Discussion:Bauer，Dymling，Hoffenberg，McCance，Querido424

General Discussion:427

Introduction:Some endocrine aspects of growth and bone＆by T．R．C．FRASER427

Bauer，Fraser，Tanner431

The effects of anabolic steroids on liver function＆by I．M．ARIAL434

Discussion:Arias，Dreyfus，Gross，Leathem，Mandema，Overbeek，Subramaniam，Vermeulen446

Anabolic steroids in the treatment of renal failure＆by J．HESS THAYSEN450

Discussion:Aschkenasy，Labhart，McCance，Querido，Thaysen，Waterlow479

Action of anabolic steroids on red-cell production＆by R．W．RUNDLES482

Discussion:Arias，Aschkenasy，Desaulles，Gemzell，Gross，Kassenaar，Leathem，Mandema，Prader，Rundles488

Concluding Discussion:494

Desaulles，Dreyfus，Korner，Laron，Leathem，McCance，Overbeek，Preader，Querido，Raben，Thaysen，Tremolières，Wilson494

Summing up＆by F．G．YOUNG500

List of authors506

Subject index507